Perfil clínico-epidemiológico dos pacientes com hiperparatireoidismo secundário acompanhados em um ambulatório de referência de Salvador, BA, Brasil

Abstract

Introduction: secondary hyperparathyroidism (HPT) is one of the common complications in dialysis patients and is characterized by hyperplasia of the parathyroid glands, elevated parathyroid hormone serum levels and a high-relocation bone disease. Objective: due to the importance of the pathology and the great impact on the morbidity and mortality of these patients, the present study aims to describe the clinical and epidemiological profile of patients with HPT in a reference outpatient clinic in Mineral and Bone Disorder (MBD). Method: a descriptive observational epidemiological study with a retrospective cross - sectional design of the entire population of patients on dialysis, conducted to first care in MBD reference outpatient clinic in the State of Bahia from January 1, 2013 to December 31, 2014. Results: of the 182 patients elected, 58.24% of the individuals were male; the median age was 46 (± 12 years) years; 28% had systemic arterial hypertension as the cause of chronic kidney disease; the median dialysis time was 84.79 (± 52.16) months; 60.77% underwent dialysis in Salvador and 50.55% were asymptomatic. Sevelamer hydrochloride was the medicine most used by the patients, representing 75.82% of prevalence. Hyperphosphatemia was verified in 54.6% of the population; 75.29% had equal and/or above 300U/L alkaline phosphatase (AF) values and 90.66% had parathyroid hormone (PTH) above 600 pg/mL. Conclusion: a population with severe HPT was evidenced, which requires a need to promote continued education of medical doctors, a better disclosure of clinical protocols, and the need to provide and deliver new therapies.